2015 Company Profiles: Probiotics International Ltd. (Protexin)
Probiotics International Ltd (Protexin)
Somerset, U.K., TA13 5JH
The Gold-Standard Probiotic Manufacturer
Protexin, a division of Probiotics International Ltd., is a vertically integrated company dedicated to producing innovative, research based probiotic products for health, such as the popular multi-strain probiotic range, Bio-Kult.
Commitment to Quality
Protexin’s purpose built manufacturing facility in Somerset U.K. has been awarded cGMP (current good manufacturing practice) (MHRA) and ISO 9001:2008 status.
This allows the company to be in complete control over its products and manufacture to the highest quality standards.
All of the ingredients Protexin uses are assessed prior to arrival at its factory, so that the company knows exactly what it is receiving. Protexin controls how the product and packaging are made and test all batches produced. All of this ensures that the highest quality product reaches the market. Protexin has been awarded the Queen’s Award for Enterprise in the category of International Trade and have been voted twice as a “Best Company to Work For.”
Protexin’s innovation and leadership in the market comes from developing its own research driven probiotic strains (identified with the initials PXN after each strains name) which are individual to the company alone. All strains are included in the European Qualified Presumption of Safety (QPS) list. The QPS lists were compiled by the European Food Standards Agency (EFSA) to assess the compiled evidence and confirm the safety and nomenclature of the bacteria used ensuring the most stable, effective and research based strains make it to the market place.
Focus on Research
One of the key areas of investment for us is research. A large program is in place, which not only covers existing products but new products too. Protexin works with clinical research organizations, leading universities and hospitals. This includes in-vitro, early stage development concept exploration and human clinical trials.
There are now more than 100 people employed across the company. There is a knowledgeable and committed research and technical team including Head of Research Peter Cartwright, who holds a wealth of microbiota knowledge. Also in the team is Medical Advisor, Dr. Mayur R. Joshi, technical advisor and nutritional therapist, Natalie Lamb and technical and product development manager, as well as Janine Barlow who leads new product development.
Protexin acquired the Bio-Kult range back in 2008, and since then the range has grown from the original multi-strain probiotic product to now include Bio-Kult Infantis, for infants, Bio-Kult Pro-Cyan, designed to target UTIs, and Bio-Kult Candéa, for people prone to candida infections.
Four Probiotic Myths
1. A good probiotic needs to be refrigerated – FALSE!
A good probiotic should be manufactured to the highest standards to ensure stability and viability throughout its product shelf life. Protexin’s technique is to encapsulate the beneficial bacteria (with a protective coating) during a freeze drying process. With this technique, refrigeration is not required, and the live bacteria will be protected until the end of its shelf life.
2. Probiotics get destroyed by the acidity of the stomach – FALSE!
As long as the manufacturer is advanced enough in its technology to protect the bacteria. Protexin encapsulates its bacteria during a freeze-drying process, which protects the bacteria from the harsh acid environment of the stomach and ensures they are effective throughout the whole of the gastrointestinal tract. A probiotic company such as Protexin should be able to provide you with data to prove this.
3. A Probiotic should contain more than 10 billion CFU – FALSE!
In 2009, McFarland1 stated that there is still no consensus on the most effective dose of a probiotic. He highlighted that the range of daily doses in clinical trials has ranged from 1 x 107 (10 million) to 1 x 1011 (100 billion) a day and that a dose that is found to be effective for one probiotic strain may not be effective for another.
4. Probiotics are all the same – FALSE!
Each probiotic strain has unique properties and health benefits. A product should state the genus (Lactobacillus), species (acidophilus) and finally the strain (PXN 35). A multi strain probiotic should therefore exert more positive benefits for a wider range of people and conditions. A review by Chapman et al2 in 2011 concluded that multi-strain probiotics appear to show greater efficacy than single strains.
1. McFarland LV. 2009. Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections. Anaerobe. Dec;15(6):274-80.
2. Chapman CM, Gibson GR, Rowland I. 2011. Health benefits of probiotics: are mixtures more effective than single strains? Eur J Nutr. 50(1):1-17.
Statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.