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Email: [email protected]
Website: www.davincilabs.com

Metabolic Multi

With weight management at the crux of many efforts to change a lifestyle, finding the right supplement regimen to support the process is an important step. Metabolic Multi from DaVinci Laboratories provides 38 nutrients to support overall metabolic health—including glucose balance, insulin sensitivity, lipid metabolism, free radical scavenging and normal inflammatory responses—giving your patients the opportunity to make the most of their healthy lifestyle choices.*

Metabolic Multi offers all benefits of a traditional multi, but also provides targeted support for various metabolic health factors.* One ingredient that stands out: GreenSelect Phytosome.

GreenSelect Green Tea Phytosome has been extensively studied for its antioxidant activity. In one trial, evaluating TRAP, an antioxidant parameter, a 20 percent increase of antioxidative capacity was observed in volunteers treated with the phytosome.1 The phytosome is known to exhibit superior bioavailability in comparison to the standard GreenSelect extract.2

GreenSelec, has also been studied with regard to its potential effects on metabolic syndrome and obesity, in conjunction with diet and lifestyle changes. In two clinical trials, it exhibited beneficial activity regarding metabolic health markers.3,4

“A recently developed oral formulation in the form of coated tablets (Monoselect Camellia) (MonCam) containing highly bioavailable green tea extract (GreenSelect Phytosome) was tested in obese subjects (n=100) of both genders on a hypocaloric diet. Fifty subjects were assigned to the green tea extract, plus hypocaloric diet, while the other 50 subjects followed the hypocaloric diet only. After 90 days of treatment, significant weight loss and decreased body mass index (BMI) were observed in the group taking the herbal extract (14 kg loss in the green tea group compared to a 5 kg loss in the diet-only group).”5

Metabolic Multi features a second Phytosome ingredient called Meriv Curcumin. This complex has been extensively studied for its healthy inflammatory response support and for its antioxidant activity.* Pharmacokinetic studies demonstrate a nearly 30-fold increase in bioavailability as compared to standard curcumin extracts.6,7

In a weight management program, a supplement that supports normal inflammatory responses can be valuable. Though researchers are, as yet, unsure of the exact relationship between chronic inflammation and obesity, it is known that metabolic syndrome is accompanied by an inflammatory condition.8 Curcumin has been studied for its potential to support normal insulin resistance. It may provide support for a normal inflammatory response through a mechanism of PPAR-gamma activation.9

Also featured in Metabolic Multi: Purple Tea with GHG. This emerging variety of Camellia sinensis, grown in Kenya, was developed with high levels of anthocyanins. Specifically, it contains the polyphenol 1,2-di-Galloyl-4,6-Hexahydroxydiphenoyl–D-Glucose (GHG), a compound not found in green, black or oolong tea.

GHG supports fat metabolism, and Purple Tea with GHG has been shown in two small, unpublished, open-label human clinical studies to support body composition and weight loss.* Research suggests the polyphenols may support lipase activity in the pancreas, as well as normal fat absorption.10,11

Other extensively researched ingredients in Metabolic Multi from DaVinci include, berberine to support normal insulin sensitivity, trans resveratrol to support glucose balance and vitamin D to support healthy expression of NF-Kappa B inflammatory cytokines.*

The ingredients mentioned here are just six of 38 important ways Metabolic Multi offers support for a weight management protocol.*

For more information, visit www.davincilabs.com.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

References:
1 Pietta, P., Simonetti, P., Gardana, C., Brusamolino, A., Morazzoni, P., & Bombardelli, E. (1998). Relationship between rate and extent of catechin absorption and plasma antioxidant status. Iubmb Life. doi:10.1080/15216549800204442.
2 Pietta, P., Simonetti, P., Gardana, C., Brusamolino, A., Morazzoni, P., & Bombardelli, E. (1998). Relationship between rate and extent of catechin absorption and plasma antioxidant status. Iubmb Life. doi:10.1080/15216549800204442.
3 Greenselect Phytosome for Borderline Metabolic Syndrome. (n.d.). Retrieved from www.hindawi.com/journals/ecam/2013/869061/.
4 Menghi, A. B., Barreca, A., Lucarelli, M., & Calandrelli, A. (0). GreenSelect Phytosome as an Adjunct to a Low-Calorie Diet for Treatment of Obesity: A Clinical Trial.
5 Menghi, A. B., Barreca, A., Lucarelli, M., & Calandrelli, A. (0). GreenSelect Phytosome as an Adjunct to a Low-Calorie Diet for Treatment of Obesity: A Clinical Trial.
6 Cuomo J. et al., J Nat Prod. 2011 Mar 17.
7 Marczylo T.H. et al., Cancer Chemother. Pharmacol. 2007, 60 (2), 171-7.
8 Monteiro, R., & Azevedo, I. (2010). Chronic Inflammation in Obesity and the Metabolic Syndrome. Mediators of Inflammation, 2010, 289645. doi:10.1155/2010/289645.
9 Mechanism of the Anti-inflammatory Effect of Curcumin: PPAR-gamma A… – PubMed – NCBI. (n.d.). Retrieved from www.ncbi.nlm.nih.gov/pubmed/18274631?dopt=abstract.
10 Unpublished study. Research and Development Department, Oryza Oil and Fat Chemical Company, Ltd. 2014 May 12.
11 Unpublished study. Research and Development Department, Oryza Oil and Fat Chemical Company, Ltd. 2014 March 1.