Sonoran University of Health Sciences (Tempe, AZ) has announced the launch of a fully remote, randomized, double-blind clinical study evaluating a topical botanical formula for recurrent cold sores. The trial will assess how natural formulations may support self-reported skin comfort and appearance in adults prone to cold sores.
The 26-week study requires no clinic visits. Instead, all participation will take place at home through the Alethios virtual human health research platform, designed to streamline participant experience. Enrolled individuals will complete short daily check-ins and, if a cold sore episode occurs, will apply an assigned topical ointment for 10 days while tracking progress with photos and surveys.
“This study reflects our commitment to advancing integrative health solutions with rigorous, patient-friendly research methods,” said Katie Stage, ND, RH (AHG), FABNG, principal investigator, at Sonoran University’s Ric Scalzo Institute for Botanical Research. “We pair state-of-the-art molecular biology and phytochemistry with the traditions of clinical herbalism to develop evidence-based botanical formulations. Building on that approach, this virtual trial lowers the barriers for participation and ensures real-world evidence on outcomes that matter most to patients.”
By comparing two university-developed natural formulations against both an over-the-counter treatment and a placebo, this study is designed to set a new benchmark for evaluating cold sore care. The rigorous double-blind design ensures the findings will be credible, unbiased and meaningful for both patients and the broader health community.
Those who meet study requirements and complete adherence tasks will receive a $25 Amazon gift card as compensation for their time. The deadline to apply is July 1.
Those interested in applying to participate in the trial, can visit https://app.alethios.com/study/c4f9149f-d1e3-470e-bdcf-b31f14c1e0ae/prescreener.
For more information, visit www.sonoran.edu/research/ric-scalzo-institute/.
