Having studied and treated these conditions for almost 50 years, since a nasty viral syndrome triggered my fibromyalgia and left me homeless in 1975, it’s been both a blessing and a challenge to see so many treatments.

On the plus side, most cases can be effectively treated (by natural practitioners). On the other hand, sorting through the options can be quite challenging.

This is usually the case as we learn about complex conditions. As we get closer to the truth, we can tell because things start to tie together and get simpler.

This is happening now. Research is showing the missing link that is common to so many common conditions. Including postinfectious CFS/fibromyalgia (which includes Lyme disease and long COVID), chronic pain of almost every type, sensitivities and MCAS (mast cell activation syndrome), and POTS (postural orthostatic tachycardia syndrome).

About 30 years ago, I investigated a natural compound called PEA (palmitoylethanolamide) for MCAS. There was a little research, but not enough to impress me. It took me three decades to decide to revisit it. As each study laid a “breadcrumb trail” for me to follow, it painted an amazing story. One that was so fascinating, it kept me up till four in the morning pulling study after study. The gist?

PEA Power

When stress from chronic pain or numerous other triggers occurs, the brain makes PEA to manage these. When the PEA gets depleted, it triggers numerous shock waves. We see sensitivities (including MCAS); microglial activation (brain inflammation and pain) which dramatically amplifies pain and causes it to become chronic; and it causes hypothalamic dysfunction (a key player in CFS/FMS/long COVID/chronic Lyme and POTS).

Giving PEA supports healing for all of these.

For chronic pain, I have not seen any natural or prescription options with this massive level of research proven efficacy. The research using it for MCAS and microglial activation is also convincing. As is the research tying all these together.

Treatment Is Simple

The keys? Use a high absorption form, preferably combined with serratiopeptidase to address commonly accompanying biofilms. In my practice, I have found PEA Healthy Inflammation Response by EuroMedica to work brilliantly.

The most common dose used in the studies is 300 mg twice daily. But let people know it can take three months to see the full effect (although it can be seen in days in some cases).

The Protocol I Use?

Although there are hundreds of studies using PEA for pain, to get a quick sense of its power I recommend you look at https://pmc.ncbi.nlm.nih.gov/articles/PMC4631430/ and an accompanying three-minute video by the prominent Netherlands pain specialist Professor Jan Keppel Hesselink (I strongly recommend you watch the video). He shares his experience using PEA in many thousands of people with severe chronic pain.

Here is the dosing Hesselink recommends:

1. He starts with PEA 600 mg twice a day in chronic discomfort, gives it a month and then goes to 1,200 mg twice a day for two months as a fair therapeutic trial.

2. Most often, he sees pain relief beginning at three weeks using this higher dosing.

This can be taken with other pain medications, and is often effective even when nothing else has worked.

So, 300 mg twice a day can be enough (for those not able to do higher dosing). But the above higher dosing will work more quickly and effectively. Then the dose can be lowered to whatever is needed to maintain the benefits (e.g. 300 to 600 mg daily or as needed)

This is a remarkable natural health care breakthrough. Chronic pain or sensitivities? POTS/FMS/Lyme? Add in the PEA. It will turn these people’s lives around!

Jacob Teitelbaum, MD, is one of the most frequently quoted post viral CFS, fibromyalgia, energy, sleep and pain medical authorities in the world. He is the author of 12 books including You Can Heal from Long Covid (June 10, 2024), the best-selling From Fatigued to Fantastic! (Penguin/Avery 2021), Pain Free, 1,2,3!, the Complete Guide to Beating Sugar Addiction, Real Cause Real Cure, The Fatigue and Fibromyalgia Solution, The Perfect Multivitamin, and the popular free Smart Phone app Cures A-Z. He is the lead author of eight studies and three medical textbook chapters on effective treatment for fibromyalgia and chronic fatigue syndrome. Dr. Teitelbaum appears often as a guest on news and talk shows nationwide including Good Morning America, The Dr. Oz Show, Oprah & Friends, CNN, and FoxNewsHealth. Learn more at www.Vitality101.com, www.EndFatigue.com and www.facebook.com/JacobTeitelbaumMD.